Processed / Duplicated Pseudogenes of Glycolytic Enzymes

Numbers of pseudogenes for each glycolytic enzyme. A dash '-' indicates that there are no processed or duplicated pseudogenes derived from a particular enzyme in a particular vertebrate genome. The chicken genome contains very few pseudogenes, the human and chimpanzee genomes contain a moderate number, and the mouse and rate genomes contain significantly more. The pseudogene copy number for GAPDH far outnumbers those of any other glycolytic enzyme.

Abbreviations: HK, hexokinase; GPI, glucose-6-phosphate isomerase; PFK, 6-phosphofructokinase; ALDO, aldolase; TPI, triose-phosphate isomerase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PGK, phosphoglycerate kinase; PGM, phosphoglycerate mutase; ENO, enolase; PK, pyruvate kinase; LDH, lactate dehydrogenase.

Processed / Duplicated Pseudogenes
  Human Chimp Mouse Rat ChickenZebrafishPufferfishFruitflyWorm
HK
1/0
1/2
0/1
-
0/2
-
-
-
-
GPI
-
-
1/0
-
-
-
-
-
-
PFK
-
-
-
-
-
0/1
-
-
-
ALDO
1/1
1/1
11/0
7/0
0/1
-
-
-
-
TPI
3/0
2/1
6/1
3/1
-
-
-
-
-
GAPDH
60/2
47/3
285/46
329/35
0/1
-
-
-
-
PGK
1/1
1/2
2/0
12/0
-
-
-
-
-
PGM
12/0
13/1
9/0
3/0
-
-
-
-
-
ENO
1/0
1/2
12/1
36/3
-
-
-
-
-
PK
2/0
3/0
10/3
4/1
-
-
-
-
-
LDH
10/2
9/1
27/7
25/4
-
-
-
-
-
Total
97
91
422
463
4
1
0
0
0

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