Yale Gerstein Lab

What Are Pseudogenes?

Pseudogenes are genomic DNA sequences similar to normal genes but are not expressed into functional proteins; they are regarded as defunct relatives of functional genes. Click here for more background information on pseudogenes and here for a list of our publications on the subject.

Pseudogene Databases

Click here to search through eukaryotic pseudogenes.
Click here to search through prokaryotic pseudogenes.
(Also available: beta-version of a new search interface for Human, Mouse and Worm pgene databases.)

Pseudogene Pipeline

Download the pipeline codes as a compressed file pgplclassic.tgz
View the pipeline README and codes online.


Worm (Caenorhabditis elegans) Fly (Drosophila melanogaster) Yeast (Saccharomyces cerevisiae) Cress (Arabidopsis thaliana)

  • Pseudogene assignments for an assortment of prokaryotic genomes are available here.

Cross-genome surveys
  • Pseudomotifs - PROSITE patterns identified in intergenic regions.
  • Composition analysis - interactive plots of amino-acid and nucleotide composition data for a variety of organisms, including pseudogenes for worm, fly, human and yeast.