Eukaryotic Pseudogenes

Analyses of Cytochrome c (cyc) Pseudogenes in Human Genome

We have identified over 49 cytochrome c (cyc) pseudogenes in the August 2001 freeze of the human genome draft.
Relevant data and results can be found here.

Publications

Zhang and Gerstein Gene (2003)

Resources

Human cyc gene in GenBank
FASTA files containing the amino acid sequences, CDS DNA sequences, and mRNA sequences of selected eukaryotes.
Alignment of amino acid sequences and underlining nucleotide sequences of cyc from selected eukaryotes
Comparative analysis of cyc by Banchi et al. and Grossman et al.
Previously identified human cyc pseudogenes in GenBank (some are redundant).

Results

Annotation file (Excel, .txt), which lists the location, length et al. on each cyc pseudogene.
Predicted amino acid sequences of cyc pseudogenes and alignment ( .txt , Excel).
Nucleotide sequence of protein coding sequence (CDS) of cyc pseudogenes and alignment.
Alignment of 5' UTR and 3' UTR sequence of human cyc pseudogenes.
Chromosome mapping of the cyc pseudogenes.
A phylogenetic tree of the pseudogenes constructed using MEGA2.
Amino acid sequence alignment of the pseudogenes with disablement highlighted.
Classification of cyc pseudogenes based on sequences at 9 codon positions.
Comparison of codon sequences between pseudogene HCP9 and rodent testis-specific cyc genes.
A flowchart of pseudogene discovery procedures.